منابع مشابه
Liver, Bio-Artificial
The liver is one of the most complex and metabolically active organs in the body and performs many detoxification and protein synthetic functions that are essential to life. Extracorporeal bioartificial liver (BAL) systems consisting of functioning, viable hepatocytes may provide temporary support for patients with acute hepatic failure and save the lives of patients awaiting orthotopic liver t...
متن کاملArtificial liver support systems.
Though artificial support systems for kidney failure have been widely available for the past several decades, it is only recently that they have become a promising treatment modality for liver failure. The various liver support systems include conventional dialysis, charcoal hemoperfusion, high volume plasma exchange, liver dialysis using sorbent technology, molecular readsorption recirculating...
متن کاملMice with artificial human liver.
‘‘Humanized’’ mice offer a window into aspects of human physiology that are otherwise inaccessible. The best available methods for liver humanization rely on cell transplantation into immunodeficient mice with liver injury but these methods have not gained widespread use due to the duration and variability of hepatocyte repopulation. In light of the significant progress that has been achieved i...
متن کاملTrials and tribulations with artificial liver support.
This paper reviews the experience gained over the past few years in two techniques of liver support, charcoal haemoperfusion and polyacrylonitrile membrane haemodialysis. Problems with charcoal haemoperfusion have centred around platelet aggregation and hypertension, and new carbon preparations with a variety of different coatings to overcome these problems are described. Haemodialysis using th...
متن کاملArtificial liver support: potential to retard regeneration?
HYPOTHESIS The concept of an "artificial liver" has been in development for over 40 years. Such devices aim to temporarily assume metabolic and excretory functions of the liver, with removal of potentially hepatotoxic substances, thereby clinically stabilizing patients and preventing deterioration while awaiting transplantation. If sufficient numbers of viable hepatocytes remain, regeneration a...
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ژورنال
عنوان ژورنال: JAPANES JOURNAL OF MEDICAL INSTRUMENTATION
سال: 1983
ISSN: 0385-440X,1881-4875
DOI: 10.4286/ikakikaigaku.53.2_83